WebMar 1, 2024 · Cisplatin-related ototoxicity is a critical side effect of chemotherapy and can lead to irreversible hearing loss. This study aimed to assess the potential effect of the DNA methyltransferase (DNMT) inhibitor RG108 on cisplatin-induced ototoxicity. ... RG108 and LY294002 were purchased from Selleck Chemicals (Houston, TX, USA) and initially ... WebFeb 27, 2024 · Normal organoids were cultivated with 20 μM or 100 μM Cisplatin for 48 hours (hrs) and 72 hrs for cytotoxicity evaluation. Cancer and normal parental organoids were maintained in culture with 10...
N-acetylcysteine ameliorates cisplatin-induced renal senescence …
WebCisplatin (cisplatinum, cis-diamminedichloroplatinum II, CDDP) is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts in tumor … WebAug 24, 2024 · Cisplatin (CDDP) remains one of the most widely used first-line drugs in the therapy of NSCLC, based on the clinical data that the poor outcomes of untreated NSCLC patients (5% overall survival... india electricity generation capacity
Cisplatin Ddp Selleck Chemicals Bioz
WebJun 9, 2024 · Overlaying single cell readouts of cell cycle and apoptosis onto a multidimensional analysis of pulsed cisplatin signalling dynamics reveals targetable mechanisms of platinum resistance in lung adenocarcinoma. ... Selleck Chem: S1009: Chemical compound, drug: MK-2206 2HCl: Selleck Chem: S1078: Chemical compound, … Webシスプラチン (Cisplatin (NSC 119875, Cisplatinum, cis-diamminedichloroplatinum II, CDDP, cis DDP, DDP)) は無機白金錯体であり、腫瘍細胞中において DNA 付加物を形成することにより DNA 合成 を阻害する能力を有します。 シスプラチンは フェロトーシス (ferroptosis) を活性化し、 オートファジー (autophagy) を誘導します。 溶液は都度調製してくださ … WebOct 15, 2024 · Cisplatin and olaparib were purchased from Selleck. Cisplatin was dissolved in water at a stock concentration of 2 mM, aliquoted into 100-μl aliquots, and stored in a −80°C freezer. Each stock vial was … india electronics \\u0026 semiconductor association