WebMouse IP LD50 40 mg/kg No data available. Material Name: Cisplatin Injection Sodium chloride Molecular Formula: Rat Oral LD50 3000 mg/kg Mixture Mouse Oral LD50 4000 mg/kg Version: 1.0 Cisplatin Mannitol Molecular Weight: Rat Oral LD 50 13500 mg/kg … WebThese human neoplastic cells are also more susceptible than peripheral blood mononuclear cells (PBMCs) toward the tested compounds. Using C57BL/6 mice an LD50 of 55mgkg(-1) was determined for complex (2), suggesting that this compound is almost four times less toxic than cisplatin (LD50=14.5mgkg(-1)).
Combination therapy of cisplatin with cilastatin enables
WebThe widespread outer hair cell lesions that develop in mice treated with cisplatin plus furosemide could serve as extremely useful murine model for investigating techniques for regenerating outer hair cells, studying the mechanisms of cisplatin and furosemide … WebOct 1, 2024 · Cisplatin is a potent chemotherapeutic used for the treatment of many types of cancer. However, its dose-limiting side effect is nephrotoxicity leading to acute kidney injury (AKI). Patients who develop AKI have an increased risk of mortality and are more likely to develop chronic kidney disease (CKD). greenbrier international universal remote
The effect of different doses of cisplatin on the …
WebOct 1, 2024 · In addition, significant immune cell infiltration was observed in the kidney after four doses of 9 mg/kg cisplatin, contrary to what has been previously reported. These results indicate that multiple strains of mice can be used with our repeated low-dose … WebMar 15, 2016 · Cisplatin at 25 mg/kg in PBS (200 μl/animal) was administered by an intraperitoneal injection. Seventy-two hours after cisplatin injection, these mice were euthanized. Another cohort of mice received either 7 or 9 mg/kg cisplatin administered by an intraperitoneal injection once a week for 4 wk. WebMaterial Name: Cisplatin Solution for Injection - 0.5 and 1 mg/ml Trade Name: Platamine; Cisplatino; Cisplatine; Platiblastin; Plastisil; Platiblastin S Chemical Family: Mixture Intended Use: Pharmaceutical product used as Antineoplastic 2. COMPOSITION/INFORMATION … greenbrier international wholesale